Luca Valenti, MD June 12th 1975, Milan, Italy TEACHING ACTIVITIES 2009 – Lecturer, Internal Medicine, Medicine degree, Università degli Studi di Milano, Italy 2009 – Lecturer, Human Pathophysiology, Medical Biotechnologies degree, Università degli Studi di Milano, Italy 2009 – Elective courses: “Genetics in hepatology”, “Metabolic liver diseases”, “Transfusion Medicine” residency in “Internal Medicine and Metabolic Diseases”, “Internal Medicine and Transfusion Medicine” Faculty of Medicine, Università degli Studi di Milano, Italy CLINICAL DUTIES - Since 2019, I coordinate the activity of the Internal Medicine and Hepatology service, Department of Transfusion Medicine and Hematology (clinical, ultrasonography and fibroscan service), clinical trials in the NAFLD field, and I set up a clinical multidisciplinary program for the screening and prevention or cardiometabolic, hepatic and neoplastic disorders in individuals with dysmetabolism in the POLIMI cohort. I set up the next-generation sequencing diagnostics for identifying genetic mutations responsible for rare hepatic and lipid metabolism disorders, and for blood antigen typing at the Fondazione IRCCS Ca’ Granda. INSTITUTIONAL RESPONSIBILITIES 2008 – Faculty member, Medicine and Surgery, Università degli Studi di Milano, Italy 2011 – 2017 Scientific Committee, Fondazione IRCCS Ca’ Granda Policlinico, Milan, Italy 2011 – 2015 Organizer of “Ca’ Granda Seminars in Molecular Medicine”, and of internal seminars “Lunch sessions”, Fondazione IRCCS Ca’ Granda, Milan, Italy 2012 – Scientific Committee, Dept. of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy 2013 – 2017 Board member of the Ph.D. School “Clinical and Experimental Medicine”, Università degli Studi di Milano, Milan, Italy 2017 - Member of the Committee for the supervision of experimental animal research, Fondazione IRCCS Ca’ Granda, Milan, Italy 2017 - Coordinator of Internal Medicine training for Medical Specialization Schools, University of Milan 2021 - Genomic and Bioinformatic Platform Scientific Board, Fondazione IRCCS Ca’ Granda FELLOWSHIPS AND AWARDS 2006 Italian Society of Internal Medicine (SIMI) Research Prize 2012 Italian Association for the Study of Liver Diseases (AISF) Prize for the Best Italian Paper in Hepatology 2010 2017 - Scientific National Habilitation (ASN), Italy, Full Professor of Internal Medicine and Full Professor of Gastroenterology SCIENTIFIC ACTIVITY My main research interest is to understand the genetic and molecular basis of liver disease, and to apply these discoveries to prevent, diagnose and treat more effectively liver disorders (both common and rare diseases), through the identification of novel biomarkers and the development of advanced precision medicine targeted therapeutic approaches. I also focused on the impact of dysmetabolism on the outcome of viral diseases, and on the role of altered iron metabolism in the pathogenesis of chronic degenerative conditions. I use a variety of tools ranging from genomic studies in large cohorts of healthy individuals and patients with metabolic liver disease with extensive phenotypic characterization (the European Liver Biopsy Cohort and Italian EPIDEMIC cohort, and the Fondazione Genomic study, a population based cohort, and Liver Bible, a multi-OMICs characterized cohort of individuals with dysmetabolism I set up at the Fondazione Biobank), to human and molecular genetics with generation of in vitro multilineage 3D models of disease by genome editing, to understand how genetic variation leads to phenotypic manifestations. In the iron field, I have contributed to establishing the role of body iron accumulation in the pathogenesis of metabolic and cardiovascular complications of insulin resistance, and I am contributing to evaluate the therapeutic utility of iron depletion and the modulation of iron pathways for the prevention of metabolic diseases. During the last five years, I more robustly establis show More

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Evolution over the last 10 years of activity
Aggregated career metrics
840

Total documents

3.66

Normalized Impact

254

Highly Cited Papers (10%)

32.14

International Collab. (%)

Most cited publications


Main coauthors


Following you can review Luca's accomplishments in each of the dimensions.

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Dimensions One by One

Spanning 73 diverse indicators, the dimensions considered capture a comprehensive spectrum of academic attributes. Each dimension includes a set of indicators and has a especific weight on the One Index. More information here...

Activity

978
/1000
Reflects an author's research output.

Impact

955
/1000
Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Excellence

965
/1000
Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Leadership

756
/1000
Reflects an author's efforts and commitment in leading research initiatives.

Cooperation

916
/1000
Reflects a researcher's ability to navigate and thrive in varied academic and research environments, highlighting adaptability, resourcefulness, and the capacity to build and maintain collaborative relationships across the spectrum of their career.

Openness

965
/1000
Reflects an author's commitment to making their research freely accessible and open to the public.

Community Support

717
/1000
Reflects an author's contributions to the academic community beyond their own research.

Community Recognition

494
/1000
Reflects the academic community's acknowledgment and appreciation of an author's contributions.

Transference

0
/1000
Reflects an author's commitment to making their research a practical application and real-world impact of an author's research.

Fundraising

0
/1000
Reflects an author's ability in securing project funding from major global entities, showcasing your ability to drive research initiatives forward.

All indicators

Performance

Activity

Reflects an author's research output.

Documents 840 Count of all document types.
Docs/Year 14.74 Average of documents published by author per year.
Citable docs 749 Count of journal articles, proceeding papers and reviews.
Journal Articles 666 Documents published as articles in scientific journals usually peer-reviewed.
Conferences 5 Original article reporting data presented at a conference or symposium.
Reviews 78 Review papers authored by the researcher.
Patents 0 Intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention.
Theses 0 Document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings
Books 0 A whole monograph or the entire book.
Book Chapters 0 Complete chapter in a book or book series volume where the item is identified as a chapter by a heading or section indicator.
Datasets 2 Number of dataset where the author have contributed to the creation.
Editorials 8 Papers where the author contributed editorial content.
Reports 0 Research reports or white papers authored.
Grants 0 Research projects funded through external grants awarded to the author.
Pre-Prints 17 Number of publications freely available in pre-print format.
Clinical Trials 1 Number of clinical trials where the author has participated.
Other types 0 Other type of documents.

Impact

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Citations 39522 Total number of citations to all the publications attributed to the author (all types).
Self Citations 2333 Citations where the author references their own previous work.
Self Citation Rate 5.903 Percentage of self-citations in the author's total citation count.
Non Self Citation Rate 94.097 Percentage of citations received from sources that are not self-citations.
Hot Citations 2527 Total number of citations recieved in the last 6 months.
Citations/Document 47.05 Average of citations recieved per document.
% Not Cited 0.0 Percentage of documents with no citations recieved.
Relative Citation Index 3.656 Item oriented indicator consisting of the quotient between the number of citations to a given work and the average number of citations to works of the same type, year and discipline. An author's RCI corresponds to the average of the values of his/her publications.
Journal Relative Citation Index 2.708 Item oriented indicator consisting of the quotient between the number of citations to a given work and the average number of citations to works of the same type, year and journal. An author's RCI corresponds to the average of the values of his/her publications.
H Index 91 Maximum value of h such that the given author has published at least h papers that have each been cited at least h times.
G Index 185 Maximum value of g such that the given author has published at least g papers that have each been cited at least g^2 times.
i10 Index 344 Number of documents with at least 10 citations recieved.

Excellence

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Citation Score 0.54 Ratio between 0 and 1 being 0 corresponding to the citation percentile being 0 the 0th and 1 the 100th.
Citation Normalized Percentile 0.525 Citation percentile normalized to 1 (0 worst, 1 best) of the position in citations rankin within the field. Provided by OpenAlex.
Higly Cited Papers (top 10%) 254 Count of publications falling on or above the 90th citation percentile in the cohort of publications of the same type, year and discipline.
Relative Higly Cited Papers 3.024 Quotient between the real number of Highly Cited Papers (HCP) and expected number of HCP's that is the 10% of total documents.
Outstanding Papers (top 1%) 56 Count of publications falling on or above the 99th citation percentile in the cohort of publications of the same type, year and discipline.
Relative Outstanding Papers 6.667 Quotient between the real number of Outstanding Papers (OP) and expected number of OP's that is the 1% of total documents.
Outstanding Papers (top 0.1%) 7 Count of publications falling on or above the 99.9th citation percentile in the cohort of publications of the same type, year and discipline.
Hot Papers 55 Using only the citations recieved in the last 6 months: documents falling on or above the 99th citation percentile in the cohort of publications of the same type, year and discipline.

Interaction within community

Leadership

Reflects an author's efforts and commitment in leading research initiatives.

Docs Leadership 369 Number of documents lead by the author.
% Leadership 43.93 Percentage of documents lead by the author.
Docs International Leadership 81 Number of documents in international collaboration lead by the author.
% International Leadership 9.64 Percentage of documents in international collaboration lead by the author.
Principal Investigator 0 Number of times where the author served as the lead researcher in a project.
Associations Founded 0 Number of associations founded by the author.
Societies Founded 0 Number of scientific or professional societies established by the author.
Foundations Founded 0 Number of research-related foundations established by the author.
Councils 0 Number of councils founded by author.

Cooperation

Reflects a researcher's ability to navigate and thrive in varied academic and research environments, highlighting adaptability, resourcefulness, and the capacity to build and maintain collaborative relationships across the spectrum of their career.

Authors/Paper 32.35 Average number of authors per document.
% Highly Authored Papers 12.14 Percentage of documents with 25 or more authors.
Countries/Paper 2.11 Average number of different countries in the author's affiliation line per document.
Docs International Collaboration 270 Number of documents reporting two or more different countries in the author's affiliation line.
% International Collaboration 32.14 Percentage of documents reporting two or more diffetent countries in the author's affiliation line.

Community Support

Reflects an author's contributions to the academic community beyond their own research.

Peer Review Counts 11 Number of times the author peer-reviewed publications.
Society Membership 0 Number of societies of wich the author is a member.
Society Memberships 0 Memberships held by the author in scientific or professional societies.
Editorial Board Memberships 0 Number of journals where the author has been member of editorial board.
Panelists 0 Number of times the author have been a panelist in the European Research Council (ERC) calls.

Community Recognition

Reflects the academic community's acknowledgment and appreciation of an author's contributions.

Distinctions 0 Number of times the author have recieved a distinction for its career.
Invitations 1 Number of times the author has been invited to talks, professorships, expositions or demonstrations.
Talks 0 Number of times the author has been invited to talks.
Professorships 0 Number of times the author has been invited to professorhips.
Commissioned Reports 0 Commissioned reports done by the author.

Interaction with society

Openness

Reflects an author's commitment to making their research freely accessible and open to the public.

Open Access Documents 425 Number of documents in Open Access mode.
% Open Access Documents 50.6 Percentage of documents in Open Access mode.
Open Access Gold 89 Number of documents published in an OA journal that is indexed by the DOAJ.
Open Access Green 75 Toll-access on the publisher landing page, but there is a free copy in an OA repository.
Open Access Hybrid 90 Free under an open license in a toll-access journal.
Open Access Bronze 170 Free to read on the publisher landing page, but without any identifiable license.
Open Access Closed 415 Non Open Access documents.

Transference

Reflects an author's commitment to making their research a practical application and real-world impact of an author's research.

Patents 0 Intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention.
Advisory Boards 0 Number of advisory boards of which the author is member.
Companies 0 Number of companies created or founded by the author.

Fundraising

Reflects an author's ability in securing project funding from major global entities, showcasing your ability to drive research initiatives forward.

Funding Counts 22 Number of activities reported as funding recieved.
ERC Grantees 0 Researchers awarded grants from the European Research Council.
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