Xu, H. Eric ^PhD

Professor at Shanghai Institute of Materia Medica (SIMM)

Leading researcher with 491 publications in the last 35 years

ORCID: 0000-0002-6829-8144

Molecular Biology

Receptor Activation G Protein-Coupled Receptors Arrestin Nuclear Receptors Peroxisome Proliferator-Activated Receptors Transcriptional Regulation Functional selectivity Parathyroid hormone receptor PPARs Crystal Structures

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Dr. H. Eric Xu obtained his bachelor and master degrees in 1985 and 1988, both from Tsinghua University in Beijing, China. He then went to Duke University and the University of Texas Southwestern Medical Center, where he earned his Ph.D. in molecular biology and biochemistry in 1994. Following a postdoctoral fellowship with Dr. Carl Pabo at MIT, he moved to GlaxoWellcome in 1996 as Research Investigator I. He was promoted to Investigator II in 1999 and again to Senior Investigator in 2001. Dr. Xu joined Van Andel Research Institute (VARI) as a Senior Scientific Investigator in 2002, became a Distinguished Investigator/Professor in 2007, and served as the Director of the Center for Structural Biology and Drug Discovery and an executive committee member of VARI in 2010. In July 2010, Dr. Xu established and served as the distinguished Director of the VARI-SIMM Center for Drug Discovery at Shanghai Institute of Materia Medica (SIMM) of Chinese Academy of Sciences. He also serves as the founding Director of the Key Laboratory of Receptor Research of Chinese Academy of Sciences. Research in his group cover structures and drug discovery of nuclear hormone receptors, G-protein coupled receptors, and plant hormones. He has published over 240 papers, with over 29,000 citations. Two of his research papers on plant hormone signaling were selected as top 10 breakthroughs by Science in 2009 and by Chinese Academy of Sciences in 2014. His X-ray laser structure of the first GPCR-arrestin complex was also selected as a top 10 breakthrough by Chinese Academy of Sciences in 2016 and was recognized by the 2016 Hans Neurath Award of Protein Society and the 2016 Wuxi outstanding achievement award. Since September 2019, Dr. Xu returned to SIMM as a Full-Time Professor and a Shanghai Talent-Summit Endowed Professor at SIMM. His research at SIMM has produced three small molecule drugs that have entered clinical trials, including VV116, a nucleoside analog that has been approved for treating COVID-19 after an outstanding efficacy from a Phase 3 clinical trial in Uzbekistan. Dr. Xu was awarded with Tan Jiazhen Life Science Career Achievement Award in 2021 and the Wu Jieping - Paul Janssen Medical & Pharmaceutical Award in 2022. show More

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Evolution over the last 10 years of activity

Aggregated career metrics

491

Total documents

4.36

Normalized Impact

192

Highly Cited Papers (10%)

45.01

International Collab. (%)

Most cited publications

Main coauthors

Following you can review H. Eric's accomplishments in each of the dimensions.

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Dimensions One by One

Spanning 73 diverse indicators, the dimensions considered capture a comprehensive spectrum of academic attributes. Each dimension includes a set of indicators and has a especific weight on the One Index. More information here...

Activity

/1000

Reflects an author's research output.

Activity

Reflects an author's research output.

Score: 0 / 1000

Available data

491

All documents ^*

^*566 including 75 non countable items

413

Citable documents

14.0

Documents / year

Books

Document type

Academic output

Last 5 years

189

All documents

126

Citable documents

37.8

Documents / year

Books

Impact

/1000

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Impact

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Score: 0 / 1000

Academic Impact

35,037

Citations

4.36

Relative Citation Index

1.39

Journal Relative Citation Index

H Index

Normalized Impact

% Documents above & below the reference

Impact on Open Access (OA) vs. PayWalled documents

1,199

Self-citations

3.42

Self Citation Rate (%)

96.58

Non Self Citation Rate (%)

Trending papers

Excellence

/1000

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Excellence

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Score: 0 / 1000

Academic Excellence

192

Highly Cited Paper (Top 10%, HCP)

Outstanding Papers (Top 1%, OP)

3.91

Relative number of HCP (RHCP)

10.79

Relative number of OP
(ROP)

Normalized Excellence

Citation percentile: from 0 to 100

Citation percentile: from 99 to 100

Highly Cited Papers (Top 10% cited)

Outstanding Papers (Top 1% cited)

Leadership

/1000

Reflects an author's efforts and commitment in leading research initiatives.

Leadership

Reflects an author's efforts and commitment in leading research initiatives.

Score: 0 / 1000

171

Publications lead

37%

Correspondence author

54%

First author

27%

Last author

Publications lead per year

Subset publications

International docs

10% Top cited

1% Top cited

RCI > 1

Correspondence

First author

Last author

Reset chart

Available data

Cooperation

/1000

Reflects a researcher's ability to navigate and thrive in varied academic and research environments, highlighting adaptability, resourcefulness, and the capacity to build and maintain collaborative relationships across the spectrum of their career.

Cooperation

Score: 0 / 1000

Collaboration

45%

International collaboration

Avg. Authors / publication

1.6

Avg. Countries / publication

10% (> 25 authors)

Docs highly authored

Employments

Educations

Openness

/1000

Reflects an author's commitment to making their research freely accessible and open to the public.

Community Support

/1000

Reflects an author's contributions to the academic community beyond their own research.

Community Recognition

/1000

Reflects the academic community's acknowledgment and appreciation of an author's contributions.

Transference

/1000

Reflects an author's commitment to making their research a practical application and real-world impact of an author's research.

Fundraising

/1000

Reflects an author's ability in securing project funding from major global entities, showcasing your ability to drive research initiatives forward.

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All indicators

Performance

Activity

Reflects an author's research output.

Documents	491	Count of all document types.
Docs/Year	14.03	Average of documents published by author per year.
Citable docs	413	Count of journal articles, proceeding papers and reviews.
Journal Articles	384	Documents published as articles in scientific journals usually peer-reviewed.
Conferences	4	Original article reporting data presented at a conference or symposium.
Reviews	25	Review papers authored by the researcher.
Patents	0	Intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention.
Theses	0	Document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings
Books	0	A whole monograph or the entire book.
Book Chapters	0	Complete chapter in a book or book series volume where the item is identified as a chapter by a heading or section indicator.
Datasets	12	Number of dataset where the author have contributed to the creation.
Editorials	3	Papers where the author contributed editorial content.
Reports	0	Research reports or white papers authored.
Grants	0	Research projects funded through external grants awarded to the author.
Pre-Prints	48	Number of publications freely available in pre-print format.
Clinical Trials	N/A	Number of clinical trials where the author has participated.
Other types	0	Other type of documents.

Impact

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Citations	35037	Total number of citations to all the publications attributed to the author (all types).
Self Citations	1199	Citations where the author references their own previous work.
Self Citation Rate	3.422	Percentage of self-citations in the author's total citation count.
Non Self Citation Rate	96.578	Percentage of citations received from sources that are not self-citations.
Hot Citations	1704	Total number of citations recieved in the last 6 months.
Citations/Document	71.36	Average of citations recieved per document.
% Not Cited	0.0	Percentage of documents with no citations recieved.
Relative Citation Index	4.355	Item oriented indicator consisting of the quotient between the number of citations to a given work and the average number of citations to works of the same type, year and discipline. An author's RCI corresponds to the average of the values of his/her publications.
Journal Relative Citation Index	1.387	Item oriented indicator consisting of the quotient between the number of citations to a given work and the average number of citations to works of the same type, year and journal. An author's RCI corresponds to the average of the values of his/her publications.
H Index	89	Maximum value of h such that the given author has published at least h papers that have each been cited at least h times.
G Index	175	Maximum value of g such that the given author has published at least g papers that have each been cited at least g^2 times.
i10 Index	307	Number of documents with at least 10 citations recieved.

Excellence

Reflects an author's academic visibility and the exceptional quality and influence of their most highly cited works.

Citation Score	0.709	Ratio between 0 and 1 being 0 corresponding to the citation percentile being 0 the 0th and 1 the 100th.
Citation Normalized Percentile	0.698	Citation percentile normalized to 1 (0 worst, 1 best) of the position in citations rankin within the field. Provided by OpenAlex.
Higly Cited Papers (top 10%)	192	Count of publications falling on or above the 90th citation percentile in the cohort of publications of the same type, year and discipline.
Relative Higly Cited Papers	3.91	Quotient between the real number of Highly Cited Papers (HCP) and expected number of HCP's that is the 10% of total documents.
Outstanding Papers (top 1%)	53	Count of publications falling on or above the 99th citation percentile in the cohort of publications of the same type, year and discipline.
Relative Outstanding Papers	10.794	Quotient between the real number of Outstanding Papers (OP) and expected number of OP's that is the 1% of total documents.
Outstanding Papers (top 0.1%)	4	Count of publications falling on or above the 99.9th citation percentile in the cohort of publications of the same type, year and discipline.
Hot Papers	51	Using only the citations recieved in the last 6 months: documents falling on or above the 99th citation percentile in the cohort of publications of the same type, year and discipline.

Interaction within community

Leadership

Reflects an author's efforts and commitment in leading research initiatives.

Docs Leadership	171	Number of documents lead by the author.
% Leadership	34.83	Percentage of documents lead by the author.
Docs International Leadership	88	Number of documents in international collaboration lead by the author.
% International Leadership	17.92	Percentage of documents in international collaboration lead by the author.
Principal Investigator	0	Number of times where the author served as the lead researcher in a project.
Associations Founded	0	Number of associations founded by the author.
Societies Founded	0	Number of scientific or professional societies established by the author.
Foundations Founded	0	Number of research-related foundations established by the author.
Councils	0	Number of councils founded by author.

Cooperation

Authors/Paper	28.49	Average number of authors per document.
% Highly Authored Papers	10.18	Percentage of documents with 25 or more authors.
Countries/Paper	1.61	Average number of different countries in the author's affiliation line per document.
Docs International Collaboration	221	Number of documents reporting two or more different countries in the author's affiliation line.
% International Collaboration	45.01	Percentage of documents reporting two or more diffetent countries in the author's affiliation line.

Community Support

Reflects an author's contributions to the academic community beyond their own research.

Peer Review Counts	7	Number of times the author peer-reviewed publications.
Society Membership	0	Number of societies of wich the author is a member.
Society Memberships	0	Memberships held by the author in scientific or professional societies.
Editorial Board Memberships	0	Number of journals where the author has been member of editorial board.
Panelists	0	Number of times the author have been a panelist in the European Research Council (ERC) calls.

Community Recognition

Reflects the academic community's acknowledgment and appreciation of an author's contributions.

Distinctions	0	Number of times the author have recieved a distinction for its career.
Invitations	0	Number of times the author has been invited to talks, professorships, expositions or demonstrations.
Talks	0	Number of times the author has been invited to talks.
Professorships	0	Number of times the author has been invited to professorhips.
Commissioned Reports	0	Commissioned reports done by the author.

Interaction with society

Openness

Reflects an author's commitment to making their research freely accessible and open to the public.

Open Access Documents	371	Number of documents in Open Access mode.
% Open Access Documents	75.56	Percentage of documents in Open Access mode.
Open Access Gold	85	Number of documents published in an OA journal that is indexed by the DOAJ.
Open Access Green	114	Toll-access on the publisher landing page, but there is a free copy in an OA repository.
Open Access Hybrid	68	Free under an open license in a toll-access journal.
Open Access Bronze	103	Free to read on the publisher landing page, but without any identifiable license.
Open Access Closed	120	Non Open Access documents.

Transference

Reflects an author's commitment to making their research a practical application and real-world impact of an author's research.

Patents	0	Intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention.
Advisory Boards	0	Number of advisory boards of which the author is member.
Companies	0	Number of companies created or founded by the author.

Fundraising

Reflects an author's ability in securing project funding from major global entities, showcasing your ability to drive research initiatives forward.

Funding Counts	0	Number of activities reported as funding recieved.
ERC Grantees	0	Researchers awarded grants from the European Research Council.

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Xu, H. Eric PhD

Preview

Total documents

Normalized Impact

Highly Cited Papers (10%)

International Collab. (%)

Most cited publications

Main coauthors

The perfect present for a young Researcher!

Dimensions One by One

Activity

Activity

Available data

All documents *

Citable documents

Documents / year

Books

Document type

Academic output

Last 5 years

All documents

Citable documents

Documents / year

Books

Impact

Impact

Citations

Relative Citation Index

Journal Relative Citation Index

H Index

Normalized Impact

% Documents above & below the reference

Impact on Open Access (OA) vs. PayWalled documents

Self-citations

Self Citation Rate (%)

Non Self Citation Rate (%)

Trending papers

Excellence

Excellence

Highly Cited Paper (Top 10%, HCP)

Outstanding Papers (Top 1%, OP)

Relative number of HCP (RHCP)

Relative number of OP (ROP)

Citation percentile: from 0 to 100

Citation percentile: from 99 to 100

Highly Cited Papers (Top 10% cited)

Outstanding Papers (Top 1% cited)

Leadership

Leadership

Publications lead

Correspondence author

First author

Last author

Publications lead per year

Subset publications

Available data

Cooperation

Cooperation

Collaboration

International collaboration

Avg. Authors / publication

Avg. Countries / publication

Docs highly authored

Employments

Educations

Openness

Openness

Available data

OA documents

Community Support

Community Support

Available data

Community Recognition

Community Recognition

Available data

Transference

Transference

Available data

Fundraising

Fundraising

Xu, H. Eric ^PhD

All documents ^*

Relative number of OP
(ROP)